It is with Great Enthusiasm that Integrative PRP introduces our valued clients to our new sister company Integrative Restorative Health. As a direct response to your request and the recent accelerating market need for high quality Human Cell Tissue Products (HCT/P) we have opened a new Extracellular Matrix (EXM) division where we now offer the highest quality products available with the same exceptional service and training.

This information is provided for educational purposes only. 

The Extracellular Matrix product we provide is manufactured in the USA and harvested from the cleanest donors in the world. The manufacturer has a 20-year history of FDA compliance and excellent laboratory practices. They have completed 6 FDA audits and they are Registered with the FDA. 

In the beautiful State of Utah, there is a unique environment of mothers that live a very clean and healthy lifestyle. The Laboratory that we use, prides itself on their 100% Chain of Custody of the tissue gathering process from start to finish. 

The proprietary process begins with meticulous screening of the donor mother and father, as well as family members for several generations. In addition to routine industry screens for blood borne pathogens, they also screen for heritable and non-heritable conditions, environmental contaminants from medications, tattoos, alcohol, drugs, tobacco, and electronic vaping.  Blood testing is performed by an independent lab who complies with CLIA standards and is registered with the FDA, certified by CMS, and accredited by CAP and AABB. 

Medical records for each donor are screened for information pertaining to risk factors for relevant communicable diseases. The screening includes a medical history interview, physical examination, behavioral risk assessment and information from other sources or records which may pertain to donor suitability. Only healthy families who meet or exceed these criteria are considered. Postnatal tissue donations are promptly collected from local hospitals minutes away by their recovery specialists following a healthy cesarean birth. After processing, allografts are tested again to ensure they are free of contaminants or infection, and contain healthy, viable cells prior to cryopreservation. 

The lots are quarantined for 14 days and thoroughly tested for bacterial, communicable, and other disease contamination by a CLIA-certified lab. Additional testing is conducted in multiple phases of the process to ensure zero contamination.

Testing is very important to prevent Graft-Versus-Host Disease to ensure this is the safest HCT/P available. Listed below, are the tests performed that exceed FDA standards:  

•       Hepatitis Bs Ag       
•       Hepatitis BC Ab 
•       HTLV I/II Ab           
•       Hepatitis C Ab 
•       HIV 182 Plus O Ab 
•       CMV ab 
•       RPR (non-treponemal syphilis) 
•       HIV-1/HCV/HBV NAT (Ultrio)
•       WNV NAT 
•       14-day Quarantine testing for Bacteria and Fungus 

CRYOPRESERVATION: 

We use a unique cryopreservation technique that includes using the source’s own natural components preserved with a natural cryoprotectant to help ensure maximum functionality at time of use. This creates industry leading bioavailability. 

Most other Regenerative Biologics products just contain ‘one’ specific type of the following:

•       Umbilical Cord blood Cell
•       Umbilical Tissue Cell 
•       Placenta Cell
•       Exosomes

EXM is a cellular matrix that does not just have one specific tissue. It gathers all of the magical tissues that create life in the womb.

This is so important because it creates a natural microenvironment that prevents apoptosis, rapid cellular death. This is like using the entire coral reef instead of just using a single fish. Using the entire biological ecosystem prevents apoptosis and ensures live healthy cells that stay alive with optimal functionality and a slower attrition rate.

What also makes this HCT/P allograft unique is that the product is minimally manipulated and contains the natural postnatal source material which includes:

•     Mesenchymal Stem Cells 
•     Progenitor Cells 
•     Exosomes
•     Growth Factors 
•     Proteins  
•     Perinatal PRP

Mesenchymal Stem Cells

MSC’s share two qualifying characteristics. Firstly, all stem cells have the potential to differentiate into multiple types of cells. Secondly, stem cells are capable of unlimited self-replication via asymmetric cell division, a process known as self-renewal. Every cell in the human body originates from stem cell precursors.

ncbi.nlm.nih.gov

Progenitor Cells 

Progenitor Cells are descendants of stem cells that then further differentiate to create specialized cell types.

technologynetworks.com

Exosomes 

All tissue cells, including stem cells, produce exosomes, packaged payloads of growth factors, cytokines, and other factors destined for secretion from the cell.

cellandbioscience.biomedcentral.com

As you can see there is a tremendous amount of science, safety and screening that goes into this product, and we are happy to bring to you the best in therapies regenerative care. 

Our knowledgeable and highly trained staff, extremely competitive pricing index, and immediate availability of product makes it easy to get started

Call today to discover that these products can bring your practice to the next level in regenerative medicine.